Conceptual Model
An overview of the main classes and their property associations. Some property associations exist only upon
representation of the Table 1 data, and so we highlight instances in pink
Ontologies
Study Cohort Ontology (SCO)
Link:
https://raw.githubusercontent.com/tetherless-world/study-cohort-ontology/master/Ontologies/studycohort.owl
View the ontology documentation at:
https://tetherless-world.github.io/study-cohort-ontology/WidocoDocumentation/doc/index-en.html
Primary Classes and Definitions
- Research Study
- Definition: A scientific investigation that involves testing a hypothesis
- Immediate Superclass: None
- Example: “10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes”
- Reused From: Hasco
- Clinical Trial
- Definition: A prospective study designed to evaluate whether one or more interventions are associated with an outcome
- Immediate Superclass: Research Study
- Example: “10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes”
- Reused From: National Cancer Institute Thesarus (NCIT)
- Cohort
- Definition: A cohort is the group of subjects enrolled in a study
- Immediate Superclass: None
- Example: Randomized Cohort in “10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes”
- Reused From: The Statistical Methods Ontology (STATO)
- Study Arm
- Definition: A group or subgroup of participants in a clinical trial that receives a specific intervention/treatment,
or no intervention, according to the trial’s protocol
- Immediate Superclass: Cohort
- Example: Metformin Conventional Therapy Arm
- Reused From: None
- Study Subject
- Definition: A person who receives medical attention, care, or treatment, or who is registered with medical
professional or institution with the purpose to receive medical care when necessary
- Immediate Superclass: None
- Example: African American Male Subject in “10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes”
- Reused From: SemanticScience Integrated Ontology (SIO)
- Study Intervention
- Definition: A process or action that is the focus of a clinical study. Interventions include drugs, medical devices,
procedures, vaccines, and other products that are either investigational or already available
- Immediate Superclass: None
- Example: Metformin
- Reused From: ProvCaRe
- Subject Characteristic
- Definition: Property that summarizes important attributes of the participants enrolled in a study
- Immediate Superclass: None
- Example: Age
- Reused From: None
- Statistical Measure
- Definition: a standard unit used to express the size, amount, or degree of something
- Immediate Superclass: None
- Example: Mean
- Reused From: ProvCaRe
Accompanying Suite of Ontologies
Ontologies Reused
We group the ontologies we reuse by the purpose and the use-cases they are intended to serve, as vocabularies for.
Study Design Ontologies
Medical Ontologies
Mid-Level Ontologies
Statistical Ontologies
Ontology Prefixes